Objective: To analysis the risk factors of nonsurgical vertebral refracture by making retrospectively study about patients with osteoporotic vertebral compression fractures (OVCF) had accepted vertebroplasty.Methods: From June 2016 to December 2017, there were 161 cases of OVCF patients were treated with single-segment vertebroplasty in our department, and follow-up data including age, gender, bone density, bone cement volume, bone cement puncture route, bone cement leakage and vertebral refracture were collected.T-test and chi-square test were used to analyze the possible risk factors for postoperative vertebral refracture.Results: Among 161 patients treated with vertebroplasty, 19 of them had refracture. Among the refracture group, including 2 males and 17 females,bone density (-3.49 + 0.20) in the refracture group, and bone density (-2.95 + 0.57) in the nonrefracture group.The difference was statistically significant (t=-4.162,P<0.001).Eight patients in the refracture group had cement intervertebral leakage, 11 patients in the nonre-fracture group had cement intervertebral leakage,24 patients in the nonre-fracture group had cement intervertebral leakage, and 138 patients in the nonre-fracture group had cement intervertebral leakage. The difference was statistically significant (chi-square = 6.928,P= 0.008).However, there was no statistically significant difference in age, gender, bone cement content, fracture history, surgical method, surgical site, puncture route and other factors.Conclusions: Decreased bone density and intervertebral leakage of bone cement may be risk factors for postoperative nonoperative vertebral refracture. Therefore, reasonable anti-osteoporosis treatment should be adhered to, and intervertebral leakage of bone cement should be minimized, to reduce the occurrence of postoperative refracture.
Refracture, Risk Factors, Vertebroplasty, Osteoporosis
- Li Y,Hai Y,Li L,et al.Early effects of vertebroplasty or kyphoplasty versus conservative treatment of vertebral compression fractures in elderly polytrauma patients[J].Arch Orthop Trauma Surg,2015 135:1633–1636.
- Bae JS, Park JH, Kim KJ,et al.Analysis of Risk Factors for Secondary New Vertebral Compression Fracture Following Percutaneous Vertebroplasty in Patients with Osteoporosis[J].World Neurosurgery,2017,99:387-394.
- Zhang ZT,Fan J,Ding QF,et al.Risk Factors for New Osteoporotic Vertebral Compression Fractures After Vertebroplasty A Systematic Review and Meta-Analysis[J].J Spinal Disord Tech,2013,4(26):E150-E157.
- Sun YC,Teng MM,Yuan WS,et al.Risk of post-vertebroplasty fracture in adjacent vertebral bodies appears correlated with the morphologic extent of bone cement[J].J Chin Med Assoc,2011,74(8):357-362.
- Zhao WT,Qin DP,Zhang XG,et al.Biomechanical effects of different vertebral heights after augmentation of osteoporotic vertebral compression fracture: a three-dimensional finite element analysis[J].J Orthop Surg Res,2018,13(32)：1-10.
- Baroud G,Nemes J,Heini P,et al.Load shift of the intervertebral disc after a vertebroplasty:a finite-element study,[J].Eur Spine J,2003; 12(4): 421-426.
International Journal of Sciences is Open Access Journal.
This article is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) License.
Author(s) retain the copyrights of this article, though, publication rights are with Alkhaer Publications.