Study of the Role of Polymorphism of ACE, GP1BA, PDE4D Genes and Clinical Features in the Development of Cerebrovascular Diseases

Study of the Role of Polymorphism of ACE, GP1BA, PDE4D Genes and Clinical Features in the Development of Cerebrovascular Diseases

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Author(s)

Author(s): A. V. Anisimova, A. S. Gunchenko, A. Yu. Ikonnikova, S. S. Galkin, M. A. Avdonina, T. V. Nasedkina, Z. Abdukhalikova

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DOI: 10.18483/ijSci.1975 27 118 97-101 Volume 8 - Mar 2019

Abstract

The frequency of cerebrovascular diseases remains high in developed countries. Currently, studies are devoted to the study of factors predisposing to the development of cerebrovascular diseases, they include the study of both modified and not modified, including genetic ones. On the basis of the in Stroke center of N. I. Pirogov City Clinical Hospital №1, Moscow, two groups of patients were examined - 91 patients with chronic cerebral ischemia and 69 patients with ischemic stroke. Associations of polymorphisms of ACE, GP1BA, PDE4D genes with the course of cerebrovascular diseases were identified.

Keywords

Stroke, Chronic Cerebral Ischemia, Risk Factors, PDE4D, ACE, GP1BA

References

  1. Feigin V.L. Anthology of stroke epidemiology in the 20th and 21st centuries: Assessing the past, the present, and envisioning the future. Int J Stroke. 2019 Feb 22:1747493019832996. doi: 10.1177/1747493019832996
  2. Feigin V.L., Krishnamurthi R.V., Parmar P., Norrving B., Mensah G.A., Bennett D.A., Barker-Collo S., Moran A.E., Sacco R.L., Truelsen T., Davis S., Pandian J.D., Naghavi M., Forouzanfar M.H., Nguyen G., Johnson C.O., Vos T., Meretoja A., Murray C.J., Roth G.A.; GBD 2013 Writing Group; GBD 2013 Stroke Panel Experts Group. Update on the Global Burden of Ischemic and Hemorrhagic Stroke in 1990-2013: The GBD 2013 Study. Neuroepidemiology. 2015;45(3):161-76. doi: 10.1159/000441085
  3. Dilaveris P.E., Kennedy H.L. Silent atrial fibrillation: epidemiology, diagnosis, and clinical impact. Clin Cardiol. 2017 Jun;40(6):413-418. doi: 10.1002/clc.22667
  4. Herrington W., Lacey B., Sherliker P., Armitage J., Lewington S. Epidemiology of Atherosclerosis and the Potential to Reduce the Global Burden of Atherothrombotic Disease. Circ Res. 2016 Feb 19;118(4):535-46. doi: 10.1161/CIRCRESAHA.115.307611
  5. Wermelt J.A., Schunkert H. Management of arterial hypertension. Herz. 2017 Aug;42(5):515-526. doi: 10.1007/s00059-017-4574-1
  6. Boehme A.K., Esenwa C., Elkind M.S. Stroke Risk Factors, Genetics, and Prevention. Circ Res. 2017 Feb 3;120(3):472-495. doi: 10.1161/CIRCRESAHA.116.308398
  7. Adams H.P. Jr., Bendixen B.H., Kappelle L.J., Biller J., Love B.B., Gordon D.L., Marsh E.E. 3rd. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993 Jan;24(1):35-41

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International Journal of Sciences is Open Access Journal.
This article is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) License.
Author(s) retain the copyrights of this article, though, publication rights are with Alkhaer Publications.

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