Schistosomiasis in Sub-Sahara Africa: Causes, Consequences and Control Measures for a Leading Neglected Tropical Disease

Schistosomiasis in Sub-Sahara Africa: Causes, Consequences and Control Measures for a Leading Neglected Tropical Disease

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Author(s): Yandev Doowuese, V. N. Chigor, E. A. Eze, D. D. Akosu, A. U. Onwuka, C. N. Okorie

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DOI: 10.18483/ijSci.2103 50 220 20-27 Volume 8 - Jul 2019


This paper reviews the causes, consequences and control measures of schsistosomiasis in Sub Sahara Africa. It is a worrisome parasitic disease caused by flukes (trematodes) of the genus Schistosoma. High prevalence rates exist in most part of Africa due to many associated factors. People become infected when larval forms of the parasite (released by freshwater snails) penetrate the skin during contact with infested water. Although it is classified under the neglected Tropical diseases, it has continued to result in life threatening complications and mortalities most especially as it affects body organs. Many factors that are associated with the disease have been discussed. So far, control programmes have proven effective despite the geometric increase in human population in Africa. Large scale treatments of population groups most especially in endemic regions have been carried out. The major set back in the treatment is lack of comprehensive data on the prevalence of schistosomiasis in many populations. In spite of this, World health Organisation has rolled out guidelines and mandates on the prevention and control of schistosomiasis in sub Saharan Africa and other places. Access to safe water, improved sanitation, hygiene education, and snail control are possible control measures reported so far in literatures. The future control measure of schistosomiasis is likely to be based on the discovery and adoption of cheap novel drugs, schistosomicides and vaccines to combat the worrisome infection in the sub Saharan Africa and other places in the Tropics.


  1. Abebe, N., Erko, B., Medhin, G., Berhe, N. (2014) Clinico-epidemiologicalstudy of Schistosomiasis mansoni in Waja-Timuga, District of Alamata, northern Ethiopia. Parasit Vectors, 7:158.
  2. Adenowo, A.F., Oyinloye, B.E., Ogunyinka, B.I., Kappo, A.P. (2015). Impact of human schistosomiasis in sub-Saharan Africa. The Brazilian Journal of Infectious Diseases, 1 9(2):196–205
  3. Adeyeba, O.A. and Ojeaga, S.G. (2002). Urinary Scistosomiasis and Concomitant Urinary Tract Pathogens Among School Children in Metropolitan Ibadan, Nigeria. African Journal of
  4. Biomedical Research, 5: 103-107.
  5. Anto, F., Asoala, V., Adjuik, M. (2013). Water contact activities andprevalence of schistosomiasis infection among school-agechildren in communities along an irrigation scheme in ruralNorthern Ghana. J Bacteriol Parasitol., 4:177.
  6. Augusto, G., Nala, R., Casmo, V., Sabonete, A., Mapaco, L., Monteiro, J. (2009). Geographic distribution and prevalence of schistosomiasisand soil-transmitted helminths among school children inMozambique. Am J Trop Med Hyg., 5:799–803
  7. Berge, S., Kabatereine, N., Gundersen, S.G, Taylor, M., Kvalsvig, J.D., Mkhize-Kwitshana, Z. (2011). Generic praziquantel in South Africa: The necessity for policy change to provide cheap, safe and efficacious schistosomiasis drugs for the poor, rural population. Review. South Afr J Epidemiol Infect., 26(1):22-25.
  8. Chistulo, L., Loverde, P., Engels, D. (2004). Disease Watch: Schistosomiasis. TDR Nature Reviews Microbiology, 2:12
  9. Colley, D.G., Loverde, P.T., Savioli, L. (2001). Medical Helminthology in The 21st Century. Science, 293: 1437–1438.
  10. Corachan, M. (2002). Schistosomiasis and international travel. Clinical Infectious Disease, 35(4):446-50.
  11. Fenwick, A., Webster, J.P., Blair, L., Fleming, F.M., Zhang, Y., Garba, A.(2002). The schistosomiasis control initiative (SCI): Rationale, development and implementation from 2002-2008. Parasitology, 136(13):1719-1730
  12. Friedman, J.F., Mital, P., Kanzaria, H.K., Olds, G.R., Kurtis, J.D. (2007). Schistosomiasis and pregnancy. Trends in Parasitology, 23(4):159-64
  13. Gberikon, G.M., Aguoru, C.U. And Yandev, D. (2015). Incidence of Schistosoma haematobium
  14. and Trichomonas vaginalis Among Occupational Status of Patients Attending Some Selected Hospitals in Gboko, Benue State Of Nigeria. International Journal of Sciences, 4 (6):38-43.
  15. Gryseels, B. (1991). The epidemiology of schistosomiasis in Burundi and its consequences for control. Science Direct, 85 (5): 623-633
  16. Kiran, S. amd Jitendra, S. (2016). Current status of schistosomiasis in Sokoto, Nigeria. Parasite Epidemiology and Control, 1(3): 239-244
  17. Kosala,G. A. D., Weerakoon, G.N. Gobert, P.C., Donald, P. M.(2015). Advances in the Diagnosis of Human Schistosomiasis. Exp Parasitol.,139:24–32.
  18. Lapa, M., Dias, B., Jardim, C., Fernandes, C.J., Dourado, P.M., Figueiredo, M. (2009). Cardiopulmonary manifestations of hepatosplenic schistosomiasis. Circulation. 119(11):1518-23
  19. Leshem, E., Maor, Y., Meltzer, E., Assous, M., Schwartz, E. (2008). Acute Schistosomiasis Outbreak: Clinical Features and Economic Impact. Clinical Infectious Diseases, 47:1499-1506.
  20. Lier, T., Simonsen, G.S., Haaheim, H., Hjelmevoll, S.O., Vennervald, B.J, Johansen, M.V. (2006). Novel real-time PCr for detection of Schistosoma japonicum in stool. Southeast Asian Journal of Tropical Medicine and Public Health, 37(2):257-64
  21. Magaisa, K., Taylor, M., Kjetland, E.F., Naidoo, P.J. (2015). A review of the control of schistosomiasis in South Africa. South African Journal of Science, 111:11-12
  22. Mazigo, H.D., Waihenya, R., Mkoji, G.M. (2010). Intestinal schistosomiasis: prevalence, knowledge, attitude andpractices among school children in an endemic area of NorthWestern Tanzania. J Rural Trop Public Health, 9:53–60.
  23. Mbabazi, P., Andan, O., Fitzgerald, D.W., Chitsulo, L., Engels, D., Downs, J.A.(2011). Examining the relationship between urogenital schistosomiasis and HIV infection. PLoS Negl Trop Dis., 5(12):e1396
  24. Mcman, D.P. (2002): Current Concepts In Schistosomiasis, 346:1212–1220
  25. Meents, E.F.and Boyles, T.H. (2010). Schistosoma haematobium prevalence inschool children in the rural Eastern Cape Province SouthAfrica. S Afr J Epidemiol Infect., 25:28-9.
  26. Mohammed, A,Z., Edino, S.T., Samaila, A.A. (2007). Surgical pathology of schistosomiasis. Journal of National Medical Association, 99(5):570-574.
  27. Nkengazong, L., Njiokou, F., Asonganyi, T. (2013). Two years impact of single praziquantel treatment on urinary schistosomiasis inthe Barombi Kotto focus, South West Cameroon. J Parasit Vector Biol.,5:83–9.
  28. Nwabueze, A.A. and Opara, K.N. (2007). Outbreak of Schistosomiasis among school children in riverine communities of Delta State, Nigeria: Impact of Road and Bridge Construction. Journal of Medical Sciences, 7: 572-578
  29. Odiere, M.R., Rawago, F.O., Obok, M. (2012). High prevalence of schistosomiasis in Mbita and its adjacent islands of LakeVictoria, western Kenya. Parasit Vectors, 5:278
  30. Otuneme, G., Akinkuade, F.O., Obebe, O.O.,Usiobuegbe, O.S., Faloye, T.G., Olasebikan, O.S., Akinleye, W.A, and Koku, O.D. (2014). A study of the prevalence of Schistosoma haematobium and Schistosoma intercalatum in a rural community in Ogun State, Nigeria. South East Asian Journal of Public Health, 4(1): 67-71
  31. Ridi, A.F. and Tallima, H.A (2012). Novel Therapeutic and Prevention Approaches for Schistosomiasis: Review. Journal of Advanced Research, 4: 467–478
  32. Ross. A.G.P., Bartlet, P.B., Sleigh, A.C., Adrian, C., Olds, G.R., Li, Y., Williams, G.M And
  33. Ruberanziza, E., Mupfasoni, D., Karibushi, B. (2010). A recentupdate of Schistomiasis mansoni endemicity around LakeRweru. Rwanda Med J., 68:5–9
  34. Salawu, O.T. and Odaibo, A.B. (2013). Schistosomiasis among pregnantwomen in rural communities in Nigeria. Int J Gynaecol Obstet.,122:1–4.
  35. Seck, S.M., Sarr, M.L., Dial, M.C., Ka, E.F. (2011). Schistosoma hematobium -associated glomerulopathy. Case Report, 21(3):201-203.
  36. Senghor, B., Diallo, A., Sylla, S.N. (2014). Prevalence and intensity of urinary schistosomiasis among school children in the district of Niakhar, region of Fatick, Senegal. Parasit Vectors, 7:5.
  37. Tetteh-Quarcoo, P.B., Attah, S.K., Donkor, E.S. (2013). Urinary schistosomiasis in children – still a concern in part of the Ghanaian capital city. Open J Med Microbiol., 3:151-8.
  38. van Lieshout, L., Polderman, A.M,, Deelder, A.M, (2000). Immunodiagnosis of schistosomiasis by determination of the circulating antigens CAA and CCA, in particular in individuals with recent or light infections. Acta Trop, 77(1):69-80.
  39. Walker, M., Zunt, J.R.(2005). Parasitic central nervous system infections in immunocompromised hosts. Clinical Infectious Diseases, 40(7):1005-15.
  40. Yirenya-Tawiah, D.R., Annang, T., Otchere, J. (2013). Urinarys chistosomiasis among adults in the Volta Basin of Ghana:prevalence, knowledge and practices. J Trop Med Parasitol. 34:1-16.

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