Reconstruction of the Lineage Y Chromosome Haplotype of Napoléon the First

Reconstruction of the Lineage Y Chromosome Haplotype of Napoléon the First

Loading document ...
Page
of
Loading page ...

Author(s)

Author(s): Gerard Lucotte, Jacques Macé, Peter Hrechdakian

Download Full PDF Read Complete Article

652 1313 127-139 Volume 2 - Sep 2013

Abstract

As part of the Napoléon I Genome (NIG) project we have reconstructed, based on more than one hundred Y-STRs (Y-short tandem repeats), the complete Y-haplotype of the non-recombinant part of the Y-chromosome (NRY) of French Emperor Napoléon I (1769-1821). We already knew the allelic values at Y-markers of the Y-chromosome of Napoléon I, but only for the palindromic STR YCAIIa and b and for the non-palindromic Y-STR DYS19. The present reconstruction aims to compare the allelic values at Y-STRs of the DNA of Charles Napoléon (C.N.), the living 4th generation descendant of Jérôme Bonaparte (Napoléon I’s youngest brother), with those of Alexandre Colonna Walewski (A.C.W.), the living 4th generation descendant of Count Alexandre Walewski (the son born of the union between Napoléon I and Countess Maria Walewska). We have previously established that Napoléon I, C.N. and A.C.W. are of the same Y-haplogroup E1b1b1b2a1. The allelic values for C.N. and A.C.W. are the same for ninety-three other non-palindromic markers (belonging to ninety different STRs) and for thirty-eight other palindromic markers (belonging to fifteen different STRs); these values then constitute those deduced in the reconstruction of the allelic values of the STR markers of the Napoléon I’s Y-haplotype. Four non-palindromic STRs and two palindromic STRs have different allelic values in C.N. and A.C.W.; we have deduced the allelic value of Napoléon I for one (DYS454), and the probable allelic values for two (Y-GATA-C4 and DYS712) of these non-palindromic variable STRs. To sum up, we have established, by reconstruction of the lineage, the allelic values of the markers of Napoléon I’s Y-haplotype for a total of one-hundred and thirty-three different Y-STR markers.

Keywords

Y-chromosome haplotype, Napoléon the First, short tandem repeats

References

  1. Jehaes E, Pfeiffer H, Toprak K, Decorte R, Brinkmann B, Cassiman JJ: Mitochondrial DNA analysis of the putative heart of Louis XVII, son of Louiss XVI and Marie-Antoinette. Eur J Hum Genet 2001, 9, 185-190
  2. Lalueza-Fox C, Gigli E, Bini C, Calafell F, Luiselli D, Plotti S, Pettener D: Genetic analysis of the presumptive blood from Louis XVI, king of France. Forens Sci Int: Genetics 2011, 5, 459-463
  3. Lucotte G: A rare variant of the mtDNA HVS1 sequence in the hairs of Napoléon’s family, Invest Genet 2010, 1, 7-10
  4. Lucotte G, Thomasset T, Hrechdakian P: Haplogroup of the Y chromosome of Napoléon the first. J Mol Biol Res 2011, 1, 12-19
  5. Karafet TM, Mendez FL, Meilerman MB, Underhill PA, Zegura SL, Hammer MF: New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree. Genome Res, 2008, 18, 830-838
  6. Athey W: Haplogroup prediction from Y-STR values using a Bayesian allele frequency approach. J Genet Geneal 2006, 2, 34-39
  7. Redd A, Agellon AlB, Kearney VA, Contreras VA, Karafet T, Park H, de Knijff P, Butler JM, Hammer MF: Forensic value of 14 novel STRs on the human Y chromosome. Forens Sci Int: Genetics 2002, 130, 97-111
  8. Butler JM, Decker AE, Vallone PM, Kline MC: Allele frequencies for 27 Y-STR loci with U.S. Caucasian, Africans Americans and Hispanic samples. Forens Sci Int 2006, 156: 250-260
  9. D’Amato ME, Ehrenreich L, Cloete K, Benjeddou M, Davison S: Characterisation of the highly discriminatory loci DYS449, DYS481, DYS518, DYS612, DYS626, DYS664 and DYS710. Forens Sci Int: Genetics 2012, 4: 104-110
  10. Burgarella C, Navascués M: Mutation rate estimates for 110 Y-chromosome STRs combining population and father-son pair data. Eur J Hum Genet 2011 19, 70-75
  11. Hanson EK, Ballantyne J: Comprehensive annotated STR physical map of the human Y chromosome: forensic implications. Legal Medecine 2006, 8, 110-120
  12. Unpublished CEPH datas (CEPH 1333-01). A study based on 32841 DYS454 alleles
  13. Norved K (personal communication). The allele range and mode reported in Table 3 are based on the distribution of 70 subjects belonging to the I1 haplogroup

Cite this Article:

  • BibTex
  • RIS
  • APA
  • Harvard
  • IEEE
  • MLA
  • Vancouver
  • Chicago

International Journal of Sciences is Open Access Journal.
This article is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) License.
Author(s) retain the copyrights of this article, though, publication rights are with Alkhaer Publications.

Search Articles

Issue June 2019

Volume 8, June 2019


Table of Contents


Order Print Copy

World-wide Delivery is FREE

Share this Issue with Friends:


Submit your Paper