Comparison between the Y-chromosome STR profiles of Hughes de Bourbon and other members of the House of Bourbon

Comparison between the Y-chromosome STR profiles of Hughes de Bourbon and other members of the House of Bourbon

Loading document ...
Page
of
Loading page ...

Author(s)

Author(s): Gerard Lucotte, Bruno Roy-Henry

Download Full PDF Read Complete Article

544 1438 92-98 Volume 3 - Feb 2014

Abstract

We have obtained a high resolution Y-chromosome STR profile of Hughes de Bourbon, the French living male descendant of the Naundorff ’s family. This STR profile was compared to those of three members of the House of Bourbon recently published (Larmuseau et al, Eur J Hum Genet 2013 ; oct.9). In our own system of comparison based on 27 STRs, the Hughes de Bourbon profile is very similar to those of the other de Bourbon published, differing from them by six mutations only. Hughes de Bourbon had also the same STR of sub-terminal differentiation (S21), and belongs to the Y-subhaplogroup R1b1a2a1a1. These datas are sufficient to include Hughes de Bourbon as a member of the House of Bourbon.

Keywords

Y-chromosome haplotype, members of the de Bourbon family, single nucleotide polymorphisms, SNPs, short tandem repeats, STRs

References

  1. Jehaes E, Decorte R, Peneau et al : Mitochondrial DNA analysis on remains of a putative son of Louis XVII, King of France and Marie-Antoinette. Eur J Human Genet 2001 ; 9 : 185-190
  2. Larmuseau MHD, Delorme P, Germain P et al : Genetic genealogy reveals true Y haplogroup of House of Bourbon contradicting recent identification of the presumed remains of two French Kings. Eur J Human Genet 2013 ; oct 9 doi : 10. 1038 / ejhg. 2013. 211
  3. Gautreau C, Rahuel C, Cartron JP, Lucotte G : Comparison of two methods of high-molecular-weight DNA isolation from human leucocytes. Analyt Biochem 1983 ; 134 : 320-324
  4. Lucotte G, Ngo KY : P49, a highly polymorphic probe that detects Taq I RFLPs on the human Y chromosome. Nucl Acids Res 1985, 13 : 8285
  5. Y-DNA haplogroup R and its subclades : http://www.isogg.org/tree/ ISOGG_ HapgrpR.html
  6. Athey WT : Haplogroup prediction from Y-STR values using a Bayesian-allele-frequency approach. J Genet Genealogy 2006 ; 2 : 34-39
  7. Lucotte G, Hazout S : Y-chromosome DNA haplotypes in Basques. J Mol Evol 1996 ; 42 : 472-475
  8. Lucotte G, Loirat F : Y-chromosome DNA haplotypes in Europe. Hum Biol 1999 ; 71 : 431-437
  9. Diéterlen F, Lucotte G : Haplotype XV of the Y-chromosome is the main haplotype in West- Europe. Biomed Pharmacol 2005 ; 59 : 269-272
  10. Jobling MA. A survey of long-range DNA polymorphisms on the human Y-chromosome. Hum Mol Genet 1994 ; 3 : 107-114
  11. Y-chromosome Consortium. A nomenclature system for the tree of human Y-chromosomal binary haplogroups. Geome Res 2002 ; 12 : 339-348
  12. Myres NM, Rootsi S, Lin AA et al : A major Y-Chromosome haplogroup R1b holocene era founder effect in Central and Western Europe. Eur J Hum Genet 2011 ; 19 : 95-101
  13. Busby GBJ, Brisighelli F, Sanchez-Diz P et al : The peopling of Europe and the cautionary tale of Y chromosome lineage R-M269. Proc Roy Soc B 2012 ; 279 : 884-892
  14. Larmuseau MHD, Vanderheyden N, Van Geystelen A, van Oven M, Kayser M, Decorte R : Increasing phylogenetic resolution still informative for Y chromosomal studies on West-European populations. Forensic Sci Int Genet 2013 (http://dx.doi. org/10.1016/j.fsigen.2013.04.002)
  15. Lucotte G, Macé J, Hrechdakian P : Reconstruction of the lineage Y chromosome haplotype of Napoléon the First. Int J Sci 2013 ; 2 : 127-139
  16. Burgarella C, Navascues M : Mutation rate estimates for 110 Y-chromosome STRs combining population and father-son pair data. Eur J Hum Genet 2011 ; 19 : 70-75
  17. Lucotte G, Thomasset T, Hrechdakian P : Haplogroup of the Y chromosome of Napoléon the first. J Mol Biol Res 2011 ; 1 : 12-19
  18. Larmuseau MHD, Vanderheyden N, Jacobs M, Coomans M, Larno L, Decorte R : Micro-geographic distribution of Y-chromosomal variation in the central-western European region Brabant. Forensic Sci Int Genet 2011 ; 5 : 95-99
  19. Larmuseau MHD, Ottoni C, Raeymaekers JAM, Vanderheyden N, Larmuseau HFM, Decorte R : Temporal differenciation accross West-European Y-chromosomal cline ; genealogy as a tool in human population genetics. Eur J Hum Genet 2012 ; 20 : 434-440
  20. Redd A, Agellon ALB, Kearney VA et al : Forensic value of 14 novel STRs on the human Y chromosome. Forensic Sci Int Genet 2002 ; 130 : 97-111
  21. Rocca RA, Magoon G, Reynolds DF et al : Discovery of Western European R1b1a2 Y chromosome variants in 1000 Genomes Project data ; an online community Approach. PLOS ONE 2012 ; 7 : e41634

Cite this Article:

International Journal of Sciences is Open Access Journal.
This article is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) License.
Author(s) retain the copyrights of this article, though, publication rights are with Alkhaer Publications.

Search Articles

Issue June 2023

Volume 12, June 2023


Table of Contents



World-wide Delivery is FREE

Share this Issue with Friends:


Submit your Paper