The Mitochondrial DNA Mitotype of Sainte Marie-Madeleine

The Mitochondrial DNA Mitotype of Sainte Marie-Madeleine

Loading document ...
Page
of
Loading page ...

Author(s)

Author(s): Gerard Lucotte

Download Full PDF Read Complete Article

DOI: 10.18483/ijSci.1167 324 1236 10-19 Volume 5 - Dec 2016

Abstract

We have extracted HVR1 (HyperVariable Region 1) mitochondrial DNA (mtDNA) sequences of Ste Marie-Madeleine (3?-63?) , from one capillary bulb of one of her hairs. These hairs are conserved in a reliquary that is exhibited in the St Maximin basilica. HVR1 sequences show, reproducely twice, nine mutations : 16129G, 16187C, 16189T, 16223C, 16224C, 16230A, 16234T, 16278C and 16311T. The corresponding haplogroup is K, sub-clade K1a1b1a. As this sub-clade is the mtDNA genetic signature of ancient Jews, that confirms the Pharisian maternal origin of Marie-Madeleine indicated in some traditions.

Keywords

Mitochondrial DNA haplogroup, Marie-Madeleine, mutations in the hypervariable region 1.

References

  1. Lucotte G. A rare variant of the mtDNA HVS1 sequence in the hairs of Napoléon’s family. Investigative Genetics, 2010, 1 : 1-6.
  2. Andrews RM, Kubacha I, Chinnery PF et al. Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA. Nature Genetics, 1999, 23 : 147 (doi : 10.1038/ 13779).
  3. Lucotte G. Skin debris on the Face of the Turin Shroud : a SEM-EDX analysis. Archaelogical Discovery, 2016, 4 : 103-117.
  4. Simoni L, Calafell F, Pettener D, Bertranpetit J, Barbujani G. Geographic patterns of mtDNA diversity in Europe. American Journal of Human Genetics, 2000, 66 : 262-278.
  5. Behar DM, Metspalu E, Kivisild T et al. The matrilineal ancestry of Ashkenazi Jewry : portrait of a recent founder event. American Journal of Human Genetics, 2006, 78 : 487-497.
  6. Behar DM, Metspalu E, Kivisild T et al. Counting of the founders : the matrilineal genetic ancestry of the Jewish diaspora. PLOSone, 2008 (doi.org/ 10.1371/ journalpone.0002062).
  7. Feder J, Ovadia O, Glaser B, Mishmar D. Ashkenazi Jewish mtDNA haplogroup distribution varies among distinct subpopulations : lessons of population substructure in a closed group. European Journal of Human Genetics, 2007, 15 ; 498-500.
  8. Behar DM, Thomas MG, Skorecki K et al. Multiple origins of Ashkenazi Levites : Y chromosome evidence for both Near Eastern and European ancestries. American Journal of Human Genetics, 2003, 73 : 768-779.
  9. Herrnstadt C, Eloon JL, Fahy E et al. Reduced-median network analysis of complete mitochondrial DNA coding-region sequences for the major African, Asian, and European haplogroups. American Journal of Human Genetics, 2002, 70 : 1152-1171.
  10. Costa MD, Pereira JB, Pala M et al. A substantial prehistoric European ancestry amongst Askenazi maternal lineages. Nature Communications, 2013, 4 : 2543 ( doi : 10.138/ncomms3543).
  11. Voragine. La légende dorée. Gallimard Ed., 2004 (chap. 92).
  12. Ostrer H. Legacy : a genetic history of the Jewish People. Oxford University Press Ed., 2012.
  13. Irshai O. In The illustrated history of the Jewish people. De Lange N. Aurum Press Ed., 1997.
  14. Baasner A, Schafer C, Junge A, Madea B. Polymorphic sites in human mitochondrial DNA control region sequences : population data and maternal inheritance. Forensic Sciences International , 1998, 98 : 169-178.
  15. Lutz S, Weisser HJ, Heizmann J, Pollak S. Location and frequency of polymorphic positions in the mtDNA control region of individuals from Germany. International Journal of Legal Medicine, 1998, 111: 67-77.
  16. Pfeiffer H, Foster P, Ortmann C, Brinkmann B. The results of an mtDNA study in 1200 inhabitants of a German village in comparison to other Caucasian databases and its relevance for forensic casework. International Journal of Legal Medicine, 2001, 114 : 169-172.
  17. Fernandez E, Perez-Perez A, Gamba C et al. Ancient DNA analysis of 8000 B.C. Near Eastern farmers supports an early Neolithic pioneer maritime colonization of Mainland Europe through Cyprus and the Agean islands. PLOSone, 2014 (dx.doi.org/10.1371/journal.pgen.1004401).
  18. Vernesi C, Benedetto G, Caramelli D et al. Genetic characterization of the body attributed to the evangelist Luke. Proceedings of the National Academy of Sciences, 2001, 98 : 13460-13463.
  19. Lucotte G, David F, Berriche S. Haplotype VIII of the Y chromosome is the ancestral haplotype in Jews. Human Biology , 1996, 68 : 467-471.
  20. Thomas MG, Skorecki K, Ben-Ami H et al. Origins of Old Testament priests. Nature, 1998, 394 : 138-140.

Cite this Article:

International Journal of Sciences is Open Access Journal.
This article is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) License.
Author(s) retain the copyrights of this article, though, publication rights are with Alkhaer Publications.

Search Articles

Issue June 2023

Volume 12, June 2023


Table of Contents



World-wide Delivery is FREE

Share this Issue with Friends:


Submit your Paper