Analysis of Clinical Efficacy of Glucose and Lipid Metabolism in Children with Growth Hormone Treatment of Turner Syndrome

Analysis of Clinical Efficacy of Glucose and Lipid Metabolism in Children with Growth Hormone Treatment of Turner Syndrome

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Author(s)

Author(s): Bo Shi

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DOI: 10.18483/ijSci.1204 159 564 31-33 Volume 6 - Mar 2017

Abstract

Objective: To investigate the effects of growth hormone on Turner syndrome of glucose and lipid metabolism. Methods: 60 patients in August 2014 - February 2015 between patients with Turner syndrome treatment, all patients using recombinant human growth hormone (rhGH) treatment a year, to observe, record and compare the before and after treatment in patients with triglyceride (TG), total cholesterol (T-CHO), high density lipoprotein (HDL-C), atherogenic index (AI), fasting blood sugar (FBS), serum insulin (FINS), insulin resistance index (IRS), etc. level indicators. Results: After treatment of children AI decreased significantly, other TG, T-CHO, HDL-C, FBS, FINS and other glycolipid metabolism did not change significantly, P> 0.05. Conclusion Turner syndrome growth hormone treatment on lipid metabolism have a certain improvement, no significant effect on carbohydrate metabolism, worthy of clinical application.

Keywords

growth hormone, Turner syndrome, glucose and lipid metabolism

References

  1. Wangrui Fang, Dong Zhi-ya, Wang Wei and other growth hormone therapy Turner syndrome into effect the year-end height and its influencing factors [J] Journal of Endocrinology and Metabolism, 2011,27 (11): 901-905.
  2. Guo Song, Du Min Alliance, Chen Hongshan and other studies in patients with metabolic syndrome prevalence and associated risk factors [J] single center in Guangzhou Turner syndrome Chinese Journal of Endocrinology and Metabolism, 2014,30 (12): 1074 -1079.
  3. Clinical and cytogenetic studies of patients [J] Li Chuan, Fan Xin, Luo Jingsi etc. .148 Example Turner syndrome China Maternal and Child Health, 2014,29 (22): 3630-3633.

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International Journal of Sciences is Open Access Journal.
This article is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) License.
Author(s) retain the copyrights of this article, though, publication rights are with Alkhaer Publications.

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