Platelet-Rich Plasma Therapy with Excelents Results in the Treatment of Post-Infectious Telogen Effluvium

Author(s): Gabriella Beltrame Pintos, Gabriela Batiston Tomasi, Camila Klotz, Laura Figueiredo Villa, João Roberto Antonio, Eduardo Vilela de Andrade, Nathan Lacerda Paulo, Bianca Pansanato Osada

Telogen Effluvium is defined as diffuse hair loss without scarring of the scalp which occurs after a stressful event. The storm of inflammatory cytokines can lead to the premature interruption of the anagen phase, resulting in excessive hair loss. The diagnosis is clinical. A 67-year-old woman with a previous diagnosis of stabilized androgenetic alopecia was infected with SARS-CoV-2 and, two months later, sought dermatological care due to intense hair loss. Telogen Effluvium was diagnosed in addition to her existing condition. Treatment involved the infiltration of active agents, combined with red LED and Fraxel laser in the affected area of the scalp, alternating with intralesional Platelet-Rich Plasma (PRP) injections into the scalp. Daily use of finasteride and oral biotin, along with topical minoxidil, was also part of the therapy. The result was significant hair recovery. Further research is needed to better define treatment guidelines.

Alopecia, Telogen Effluvium, Platelet-Rich Plasma

1. Malkud S. Telogen effluvium: a review. J Clin Diagnostic Res. 2015; 9(9):WE01. DOI: https://doi.org/10.7860/jcdr/2015/15219.6492
2. Contin LA, Rocha VB. Acute telogen effluvium triad after resolution. An Bras de Dermatol. 2021; 96:605-8. DOI: https://doi.org/10.1016/j.abd.2020.10.008
3. Koç Yıldırım S, Erbağcı E, Demirel Öğüt N. Evaluation of patients with telogen effluvium during the pandemic: May the monocytes be responsible for post COVID‐19 telogen effluvium?. J Cosmet Dermatol. 2022; 21(5):1809-15. DOI: https://doi.org/10.1111/jocd.14883
4. Moreno‐Arrones OM, Lobato‐Berezo A, Gomez‐Zubiaur A, Arias‐Santiago S, Saceda‐Corralo D, Bernardez‐Guerra C, et al. SARS‐CoV‐2‐induced telogen effluvium: a multicentric study. J Eur Acad Dermatol Venereol. 2020. DOI: https://doi.org/10.1111/jdv.17041
5. Rivetti N, Barruscotti S. Management of telogen effluvium during the COVID‐19 emergency: psychological implications. Dermatol Ther. 2020; 33(4) DOI: https://doi.org/10.1111%2Fdth.13648
6. Hosking AM, Juhasz M, Atanaskova Mesinkovska N. Complementary and alternative treatments for alopecia: a comprehensive review. Skin Appendage Disord. 2019; 5(2):72-89 DOI: https://doi.org/10.1159/000492035
7. Roohaninasab M, Goodarzi A, Ghassemi M, Sadeghzadeh‐Bazargan A, Behrangi E, Najar Nobari N. Systematic review of platelet‐rich plasma in treating alopecia: Focusing on efficacy, safety, and therapeutic durability. Dermatol Ther. 2021; 34(2):e14768 DOI: https://doi.org/10.1111/dth.14768