Azoniallene Salts: Synthesis and their Utility in Heterocyclic Synthesis

Author(s): Mohamed E. Khalifa, Ahmed S. Radwan, El-Sayed H. Al-Tamany, Ehab Abdel-Latif

A series of novel 5-arylazo-thiazol-2-ylcarbamoyl-thiophene derivatives was synthesized and their chemical structures were secured by elemental and spectroscopic analyses. Their versatility for pharmaceutical purposes and textile dyeing as disperse dyes was reported. The synthesized dyes were applied to polyester fabrics by using high temperature dyeing method at 130°C. The dyed polyester fabrics, which display yellowish-brown to brown hues, were displayed excellent washing and perspiration fastness and moderate light fastness. Finally, the synthesized compounds showed biological activities against Bacillus subtilise, Staphylococcus aureus (Gram positive bacteria), Escherichia coli, Pseudomonas aeruginosa (Gram negative bacteria), while no effect had been reported against Fungi. The minimum inhabitation concentration of the most active compound was evaluated.

2-Aminothiazole, Biological activity, Disperse dyes, Fastness properties, Polyester fibers, Thiophene

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